Reviews 1 — Oral Biology

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“Education is not the filling of a pot but the lighting of a fire..”

— W.B. Yeats

Multiple Learning domain integrated Module : Module split into multiple learning domains -cognitive, effector and psychomotor domains to aid in holistic learning.Learning process go beyond reading and memorizing facts. Students are trained to critically evaluate the concepts in depth.

Sing – along learning : Concepts which are difficult to memorise are taught using the sing -along method , where the points are sung with a peppy tune created by Stomp, beatboxing and acapella. This stimulates the young minds to listen, observe and retain.

Reel – Dance learning: To break the monotony during lectures and practical schedules , a quick reel dance is done to invigorate the spirits. Reel dance involves a rhythmic pattern which needs rapt attention during performance. This method changes the vibes instantly and results in better attention in the following time period.

Curriculum - M.S Oral Biology

Advanced Oral Biology:

Ontogenesis

Evolutionary perspective of cellular development from simple molecules that were formed during first billion years of Earth to development of cells, tissues, and organs of invertebrates and vertebrates. Development of vertebrate feeding apparatus from comparative anatomical and physiological point of view, followed by embryogenesis of orofacial and dental structures of humans.

Pathobiology

Molecular basis for pathogenic processes in tissues of oral cavity. Topics include microbially mediated demineralization of hard tissues, soft tissue infections, carcinogenesis, colonization of mucosal substrates by opportunists, etc. S/U or letter grading.

Salivary Diagnostics: Salivaomics, Saliva-Exosomics, Saliva Liquid Biopsy

Focus on basic, translational, and clinical advancements of saliva and its -omics constituents in oral and systemic health, precision, and personalized medicine.

Oral Embryology and Histology

Development and histological structure of facial region and oral and peri-oral organs and tissues.

Mechanisms and Relief of Pain

Neuroanatomical, neurophysiological, and biochemical bases of pain perception. Classical pain theories, pain receptors and pathways, endogenous mechanisms of pain modulation, and pharmacological basis for treatment of pain disorders.

Current Topics in Oral Immunology

basic immunology. Immunological issues related to oral health, including HIV, opportunistic oral infections, periodontal pathology, oral immunopathology, caries immunology, endodontic immunology. Basic cellular and molecular mechanisms involved in responses mediated by immune effectors, with emphasis on immunopathology involved in autoimmunity, cancer, and immunodeficiency syndromes. Letter grading.

Genomics and Proteomics in Oral Biology Research

Fundamentals and technical aspects of genomics and proteomics and analysis of data derived therefrom. Implications and applications of genomics and proteomics in diagnostic protocols such as salivary diagnostics.

Biology of Temporomandibular Joint

Anatomy, histology, physiology, and biomechanics of temporomandibular joint (TMJ) and related musculature. Pain mechanisms, sensorimotor integration, and motor mechanisms in TMJ function, and current methods of TMJ imaging.

Osteo immunology

Oral bone biology and immunology and how both systems talk to each other. Topics include immune modulation of bone metabolism, osteoblastic niche for hematopoietic progenitors, adult bone marrow stem cell changes, and osteo immunology in at-risk populations. Letter grading.

Integrative Biology and Biomaterials Science in Relation to Dentistry

Introduction to integrative biology and biomaterials science by bringing together diversity of disciplines that complement one another to unravel complexity of biology in biomaterials in relation to dentistry. Integration of bioengineering, materials sciences, cell biology, and dentistry. Fundamentals of materials science in relation to dentistry, stem cell biology, and knowledge necessary to participate in dental and biomedical research, innovation, and product development.

Craniofacial Growth and Development

principles governing growth and development of craniofacial region.

Dental Embryology and Histology

development of orofacial apparatus and histological features of its component tissues.

Dental Pharmacology and Therapeutics

Pharmacology, with particular emphasis on how drugs interact with dentistry. General principles of drug action and drug effects on autonomic and central nervous systems.

Culture, Ethnicity, and Health: Implications for Oral Biology and Medicine

Sociocultural, biological, and linguistic anthropology to understand factors that influence health and well-being, experience and distribution of illness, prevention and treatment of sickness, healing processes, social relations of therapy management, and cultural importance and utilization of pluralistic medical systems. Theory, perspectives, and methods from clinical medicine, public health, epidemiology, demography, and social sciences.

Anthropological Perspectives on Global Health: Implications for Oral Biology and Medicine

Political ecology of infectious diseases, child health issues, women's health and reproductive health, global trade in legal and illegal drugs, demography and health transition, structural adjustment, problems associated with globalization of pharmaceutical industry; antibiotic resistance, and globalization and health equity.

Developmental Neuroendocrine immunology

Psychological and physiological processes intertwine, and one important aspect of psychoneuroimmunological research is characterization of mechanisms that underlie these interactions. Examination of current literature on neuroimmune interaction from developmental perspective.

Clinical Immunology and Lymphology

Immunology and lymphology from clinical perspective. Emphasis on immune surveillance and lymphatic drainage of oral pathologies associated with AIDS and other diseases.

Molecular and Cell Biology for Oral Biology Graduate Students

Lecture, two hours; literature review, one hour. Advanced course on prokaryotic and eukaryotic molecular and cell biology, with emphasis on applications in dental research applications in dental research.

Program Outcome - MS Oral Biology

PO1

Develop competency and proficiency in Oral Biology

PO2

Obtain Critical thinking, research and problem solving skills in Oral Biology

PO3

To ensure higher knowledge and competence in Biomaterials and tissue engineering

PO4

Understand Cognitive, Affective, Psychophysiological, and Behavioural assessments in Pain Perception

PO5

Ability to conduct Pedigree assessment in patients with Congenital Craniofacial Disorders

PO6

Ability to conduct Gene expression experiments in patients with Congenital Craniofacial Disorders

PO7

Ability to analyze Gene and proteome expression in patients with bone disorders

PO8

Ability to conduct experiments that unravel the Molecular aspects of pain mechanism

PO9

Assessment of Immune mechanisms in hard and soft tissues

PO10

Ability to do a sequential demonstration of craniofacial development in mice model

PO11

Understand genetic determinants of craniofacial development in human fetus

PO12

Ability to organize biomaterials characterization experiments

PO13

Ability to understand basics of cell culture and develop an Invitro disease model

PO14

Ability to isolate stem cells from oral tissues & stem cell induction

PO15

Validation of salivary exosomes and diagnostic challenges

PO16

To evaluate and assess Oral microbiome

PO17

Understand gene vectors and drug delivery system using Biomaterial science

PO18

Understand evolutionary biology in comparison with other animal species, To compare and correlate craniofacial anatomy with other animal species

PO19

Micro fabricated tissue-engineered models for cancer and other diseases

PO20

Understand research, literature review and updation in Oral biology

Curriculum - M.Sc Oral Biology

Biology Of Oral Tissues

Anti-microbial peptides. Structure and function of oral mucosa. Bone pathologies. Cell biology of bone. Cytoskeleton. Desmosomes and cell attachment. Introduction to stem cells. Oral defence mechanisms.

Oral Pathology & Oral Microbiome

Carcinogenesis. Acquisition and metabolism of oral flora. Oral commensal and opportunistic pathogens. Dental plaque. Disease of the salivary gland. Microbiology and periodontal disease. The mouth as a microbial habitat. Oral defence mechanisms. Oral infections. Overview of infectious agents. Pathology of pre cancer. Overview of virulence.

Dental Hard Tissues & Microenvironment

Mechanisms and underlying principles and of the diseases of dental hard tissue loss, including calcium phosphate chemistry, chemical interaction with acids, and protective role of salivary proteins How an understanding of these processes can contribute to the treatment, restoration, and ultimately prevention of these diseases.

Basics Of Minimally Invasive Dentistry

The underlying biochemical and physicochemical mechanisms of clinical dental prevention methods How protective mechanisms against hard dental tissues diseases exist in the oral environment and how these can be used to prevent the disease. The progress of hard dental tissue diseases and learn about existing and novel detection methods. How novel biomaterials are developed mimicking oral environment.

Biomineralization And Biomimetics

Mechanisms and underlying principles of biomineralisation with particular emphasis on hard tissues relevant to the oral environment such as enamel, dentine and bone formation. Also, how an understanding of these processes can lead to the development of synthetic biomaterials and biomimetic products with applications in Oral Biology.

Program Outcome MSC011 Oral Biology

PO1